Product Name: Retatrutide (Reta)
Type: Multi-Pathway Metabolic Research Peptide

Research Focus:

Retatrutide is a novel triple agonist targeting GLP-1, GIP, and glucagon receptors[1], studied for substantial weight loss and metabolic improvement in obesity and type 2 diabetes[2][3]. With an extended half-life of approximately 6 days, this peptide enables convenient once-weekly subcutaneous dosing with a gradual titration protocol to optimize tolerability[1][4].

Research Interest:

• Appetite and satiety signaling research

• Glucose metabolism pathway studies

• Fat metabolism regulation models

• Integrated metabolic control systems

Scientific Interest:

• Multi-receptor metabolic signaling networks

• Hormonal regulation of energy balance

• System-level metabolic pathway coordination

Reconstitution:

• Reconstitute: Add 2.0 mLbacteriostatic water → 5.0 mg/mLconcentration for convenient weekly doses.

• Typical weekly range: 2–12 mg once weekly (gradual escalation over 12+ weeks).

• Easy measuring: At 5.0 mg/mL, 1 unit = 0.01 mL ≈ 50 mcg on a U-100 insulin syringe.

• Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 2–4 weeks.

Cycle:

Standard / Gradual Titration Approach (2 mL = 5.0 mg/mL)

Frequency: Inject once weeklysubcutaneously. This schedule follows clinical trial protocols that demonstrated significant weight loss (up to 24% at 48 weeks with 12 mg weekly)[2] while minimizing gastrointestinal adverse events through gradual escalation[1][4]. Starting at 2 mg weekly (versus 4 mg) significantly reduces initial GI side effects. For doses exceeding 1.0 mL, either reconstitute a second vial or split the dose into multiple injection sites.

Reconstitution Steps

1. Draw 2.0 mL bacteriostatic water with a sterile syringe.

2. Inject slowly down the vial wall; avoid foaming.

3. Gently swirl/roll until dissolved (do not shake vigorously).

4. Label with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.

Note: The 10 mg vial size with 2.0 mL reconstitution provides excellent concentration (5.0 mg/mL) for convenient dosing. Lower weekly doses (2–4 mg) fit comfortably in a single syringe, while higher maintenance doses (8–12 mg) require multiple vials or split injections across different sites.

IMPORTANT NOTICE:

This product is intended strictly for laboratory research. It is not intended to diagnose, treat, cure, or prevent any disease.